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HelpCatalog ID sp100 Anti-sp100 Antibody, IgG
Additional Codes
CPOE: Ref Anti-sp100 Antibody, IgG
DOE: Ref sp100
Specimen
Gold SST tube, collect 1.0 mL blood
Centrifuge within 2 hours of specimen collection
Serum, 0.5 mL (0.1 mL minimum), refrigerated
Rejection Criteria
Plasma, heat-inactivated specimen, contaminated specimen, grossly icteric specimen, severely lipemic specimen, grossly hemolyzed specimen, inclusion of fibrin clot, insufficient quantity, unlabelled specimen, specimen not centrifuged <2 hours from collection, specimen at room temperature >48 hours after collection
Interpretative Information
SP100 IgG antibodies can be detected in patients with primary biliary cholangitis (PBC) and may be of diagnostic relevance in a subset of patients with PBC who are negative for anti-mitochondrial antibodies (AMA). These antibodies have a relatively low sensitivity with excellent specificity for PBC. A negative result does not rule out PBC.
Performing Lab
ARUP Laboratories
Turn-Around-Time
1-8 days (performed on Wednesdays)
Reference Values
| Value | Interpretation |
|---|---|
| 20.0 Units or less | Negative |
| 20.1-24.9 Units | Equivocal |
| 25.0 Units or greater | Positive |