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HelpCatalog ID dsDNA Ab dsDNA Antibody
CPT Code
86225
Specimen
1.2 mL whole blood in gold top tube. Red top also acceptable. Minimum 0.5 mL serum.
Rejection Criteria
Incorrect tube, Insufficient specimen, unlabelled specimen.
Interpretative Information
More than 90% of patient with SLE have dsDNA antibodies and the titer is a marker of disease activity.
A definitive clinical diagnosis should not be based on the results of a single diagnostic method, but should only be made by the physician after all clinical and laboratory findings have been evaluated. This assay has a specificity of 97.0% and a sensitivity of 87.3%.
Performing Lab
Immunology Laboratory, Core Lab - AD3301, x1-3378
Turn-Around-Time
1-3 business days
Reference Values
<10 U/mL = Negative
10-15 U/mL = Equivocal, repeat in 8-12 weeks
>15 U/mL = Positive