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HelpCatalog ID Titer Antibody Titer in Transfusion Service
CPOE Test Name
Antibody Titer, Titer
Synonyms
Antibody titer, isohemagglutinin titer (Anti-A or Anti-B titer) prenatal titer, Rh titer, atypical antibody titer, AHG titer, IgG titer.
Specimen Requirements
Samples require Name, MRN, date and phlebotomist initials/Cerner ID. Pink top (EDTA) tube. Indicate in Comments what type of titer is being requested: ABO or atypical antibody.Storage and Transport
Send to Blood Bank
Causes for Rejection
Improper labeling; wrong tube; gross hemolysis; insufficient volume
Interpretation
To follow antibody levels in potential maternal-fetal blood incompatibility, to assess HDN, to assess IgG isoagglutinin levels in adults or infants, to assess antibody levels in transfusion reaction, or determine antibody concentration in a serum sample containing a known clinically significant antibody.
Turn Around Time
Isohemagglutinin Titer: 30 minutes AHG Titer: 1 hour
Methodology
This is a semi quantitative method used to determine antibody concentration. The reciprocal of the highest dilution of serum giving a 1+ reaction is referred to as the titer.
CPT / HCPCS Code
86886
Reference Ranges
Reported as the last dilution resulting in a 1+ reaction. Critical value for prenatal titers are titers greater than 32.
Performing Lab
Blood Bank BI 1230 721-2732