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Catalog ID Sen Neur Sensory Neuropathy Antibody Panel with Reflex to Titer and Neuronal Immunoblot

Additional Codes

CPOE: Ref Sensory Neuropathy Antibody Panel with Reflex to Titer and Neuronal Immunoblot

DOE: Ref Sen Neur

Specimen

Gold SST tube, collect 4.0 mL blood

Centrifuge within 2 hours of specimen collection

Serum, 2.0 mL (1.0 mL minimum), refrigerated

Rejection Criteria

Plasma, other body fluids, contaminated specimens, heat-inactivated specimens, hemolyzed specimens, grossly icteric specimens, lipemic specimens, specimens not centrifuged < 2 hours from collection, specimens at room temperature >24 hours, insufficient quantity, unlabelled specimens

Interpretative Information

Aid in diagnosis of a sensory neuropathy when malignancy, other than plasma cell dyscrasia, is suspected.

Purkinje Cell (PCCA) antibody and Neuronal Nuclear (ANNA) antibody IgG are screened by IFA. If the IFA screen is indeterminate, then a Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. If the IFA screen is positive at 1:10 or greater, then a PCCA/ANNA antibodies titer and Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. Additional charges apply.

Performing Lab

ARUP Laboratories

Turn-Around-Time

2 - 9 days (performed on Tuesdays)

Reference Values

Components Reference Interval
SGPG Antibody, IgM Less than 1.00 IV
MAG Antibody, IgM Elisa Less than 1000 TU
Purkinje Cell/Neuronal Nuclear IgG Scrn None Detected