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HelpCatalog ID Ref PM-1 PM/Scl-100 Antibody, IgG by Immunoblot
CPOE Test Name
CPOE: Ref PM/Scl-100 Antibody, IgG
DOE: Ref PM/SCL100
Synonyms
PM/Scl-100, Polymyositis, PM1
Specimen Type
Gold SST tube, collect 2.0 mL blood
Serum, 1.0 mL (0.3 mL minimum), refrigerated
Causes for Rejection
Specimens other than serum, hemolyzed serum, severely lipemic specimens, contaminated specimens, insufficient quantity, unlabeled specimens
Reference Values
Negative
Performing Lab
ARUP Laboratories
Turn Around Time
6-14 business days from time of collection
Performed Tue, Thu, Sat
CPT / HCPCS Code
86235
Interpretative Data
The presence of PM/Scl-100 IgG antibody along with a positive ANA IFA nucleolar pattern is associated with connective tissue diseases such as polymyositis (PM), dermatomyositis (DM), systemic sclerosis (SSc), and polymyositis/systemic sclerosis overlap syndrome. The clinical relevance of PM/Scl-100 IgG antibody with a negative ANA IFA nucleolar pattern is unknown. PM/Scl-100 is the main target epitope of the PM/Scl complex, although antibodies to other targets not detected by this assay may occur.
Specimen Stability
Room Temperature: 48 hours
Refrigerated: 2 weeks
Frozen: 1 year