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HelpCatalog ID Ref DT Diphtheria & Tetanus Antibodies, IgG
CPOE Test Name
CPOE: Ref Diphtheria & Tetanus Antibodies, IgG
DOE: Ref DT Abs
Synonyms
Tetanus/Diphtheria IgG, D/T
Specimen Type
Serum
Specimen Requirements
Gold SST tube, collect 2.0 mL blood
Centrifuge within 2 hours of specimen collection
Serum, 1.0 mL (0.15 mL minimum), refrigerated
Storage and Transport
Serum stored refrigerated until ready for transport to ARUP Laboratory
Reference Range
Antibody concentrations of > 0.1 IU/mL are usually considered protective for diphtheria or tetanus.
Causes for Rejection
Plasma, other body fluids, specimens not centrifuged within 2 hours of specimen collection, specimens at room temperature >48 hours, insufficient quantity, unlabelled specimen
Turn Around Time
1-3 days
CPT / HCPCS Code
86317×2
Performing Lab
ARUP Laboratories
Interpretative Information
Responder status is determined according to the ratio of a one-month post-vaccination sample to pre-vaccination concentration of IgG antibodies as follows:
Diphtheria and tetanus:
1. If the post-vaccination concentration is less than 1.0 IU/mL, the patient is considered a nonresponder.
2. If the post-vaccination concentration is greater than or equal to 1.0 IU/mL, a patient with a ratio of less than 1.5 is a nonresponder, a ratio of 1.5 to less than 3.0, is a weak responder, and a ratio of 3.0 or greater, is a good responder.
3. If the pre-vaccination concentration is greater than 1.0 IU/mL, it may be difficult to assess the response based on a ratio alone. A post-vaccination concentration above 2.5 IU in this case is adequate.