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HelpCatalog ID RUFI Rufinamide, Serum
Useful For
Monitoring serum rufinamide concentrations, assessing compliance, and adjusting dosage in patients receiving other drugs that interact pharmacokinetically with rufinamide (ie, drugs that induce liver CYP3A4 enzymes) and may be helpful in those who are receiving hemodialysis
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Collect blood immediately before next scheduled dose.
2. For sustained-release formulations ONLY, collect blood a minimum of 12 hours after last dose.
3. Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Collect 2.0 mL blood in Red top tube.
Reference Values
5.0-30.0 mcg/mL
Day(s) Performed
Tuesday, Thursday, Saturday
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reporting Name
Rufinamide, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80210
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| RUFI | Rufinamide, S | 59323-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 63030 | Rufinamide, S | 59323-6 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.