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Catalog ID OSCAL Osteocalcin, Serum

Important Note

CPOE TEST NAME:   Ref Osteocalcin; REF OSCAL

Useful For

Monitoring and assessing effectiveness of antiresorptive therapy in patients treated for osteopenia, osteoporosis, Paget's disease, or other disorders in which osteocalcin levels are elevated

 

As an adjunct in the diagnosis of medical conditions associated with increased bone turnover, including Paget's disease, cancer accompanied by bone metastases, primary hyperparathyroidism, and renal osteodystrophy

 

This test is not useful for the diagnosis of osteoporosis; diagnosis of osteoporosis should be made on the basis of bone density or clinical history of low-trauma fracture.

Specimen Type

Serum


Specimen Required


Patient Preparation:

1. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

2. Fasting (12 hours)

 

Supplies: Aliquot Tube, 5 mL (T465)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


AUMC Laboratory Catalog Note:

Collect 2.2 mL blood in Red top tube.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 14 days
  Refrigerated  72 hours

Reference Values

<18 years: not established

≥18 years: 9-42 ng/mL

Day(s) and Time(s) Performed

Monday through Friday; 5 a.m.-12 a.m., Saturday; 6 a.m.-6 p.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83937

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OSCAL Osteocalcin, S 2697-1

 

Result ID Test Result Name Result LOINC Value
OSCAL Osteocalcin, S 2697-1

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Osteocalcin, S

Method Name

Electrochemiluminescence Immunoassay