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Catalog ID MuSK Muscle-Specific Kinase (MuSK) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum

Additional Codes

CPOE: Ref Muscle-Specific Kinase (MuSK) Antibody, IgG

DOE: Ref MuSK Ab

Specimen

Gold SST tube, collect 4.0 mL blood

Centrifuge within 2 hours of collection

Serum, 2.0 mL (1.0 mL minimum), refrigerated

Rejection Criteria

Plasma, grossly lipemic specimens, grossly icteric specimens, grossly hemolyzed specimens, specimen not centrifuged <2 hours from collection, specimen at room temperature >48 hours, insufficient quantity, unlabelled specimen

Interpretative Information

Muscle-specific kinase (MuSK) antibody is found in a subset of patients with myasthenia gravis, primarily those seronegative for muscle acetylcholine receptor (AChR) antibody. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of myasthenia gravis.

Performing Lab

ARUP Laboratories

Turn-Around-Time

2-8 days (performed on Mondays and Thursdays at ARUP)

Reference Values

Negative 0.00-0.03 nmol/L
Positive 0.04 nmol/L or greater