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HelpCatalog ID LALBS Lysosomal Acid Lipase, Blood Spot
Useful For
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood spot specimens
This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
Reporting Name
Lysosomal Acid Lipase, BSSpecimen Type
Whole bloodNecessary Information
Provide a reason for testing with each specimen.
Specimen Required
Supplies: Card-Blood Spot Collection (Filter Paper) (T493)
Collection Container/Tube:
Preferred: Blood spot collection card
Acceptable: PerkinElmer 226 filter paper, Munktell TFN, and Whatman Protein Saver 903 Paper
Specimen Volume: 2 Blood spots
Collection Instructions:
1. Completely fill at least 2 circles on the filter paper card (approximately 100 microliters blood per circle).
2. An alternative blood collection option for a patient older than 1 year is a fingerstick. For detailed instructions, see How to Collect Dried Blood Spot Samples.
3. Let blood dry on the filter paper at ambient temperature in a horizontal position for a minimum of 3 hours.
4. Do not expose specimen to heat or direct sunlight.
5. Do not stack wet specimens.
6. Keep specimen dry.
Additional Information:
1. For collection instructions, see Blood Spot Collection Instructions.
2. For collection instructions in Spanish, see Blood Spot Collection Card-Spanish Instructions (T777).
3. For collection instructions in Chinese, see Blood Spot Collection Card-Chinese Instructions (T800).
Specimen Minimum Volume
1 Blood spot
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Refrigerated (preferred) | 28 days | FILTER PAPER |
| Frozen | 90 days | FILTER PAPER | |
| Ambient | 7 days | FILTER PAPER |
Reject Due To
| Shows serum rings Multiple layers |
Reject |
Reference Values
≥21.0 nmol/h/mL
Day(s) Performed
Friday
Report Available
8 to 15 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82657
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LALBS | Lysosomal Acid Lipase, BS | 73958-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 62955 | Lysosomal Acid Lipase, BS | 73958-1 |
| 36341 | Reviewed By | 18771-6 |
| 36340 | Interpretation (LALBS) | 59462-2 |
Method Name
Fluorometric Enzyme Assay
Special Instructions
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602)
3. If not ordering electronically, complete, print, and send 1 of the following forms with the specimen: