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HelpCatalog ID Jo-1 Ab Jo-1 Antibody
CPT Code
86235
Specimen
1.2 mL of whole blood collected in gold top tube. Red top also acceptable. Minimum 0.5 mL of serum.
Rejection Criteria
Incorrect tube, insufficient specimen, unlabelled specimen
Interpretative Information
Jo-1 antibodies can be found as markers in polymyositis/dermatomyositis (prevalence approx. 25%) but also in patient with intestinal pneumonitis and in some children with myositis. Patients with Jo-1 antibodies tend to have a more severe form of disease with a tendency to relapse.
A definitive clinical diagnosis should not be based on the results of a single diagnostic method, but should only be made by the physician after all clinical and laboratory findings have been evaluated. This assay has a specificity of 100.0% and a sensitivity of 72.0%
Performing Lab
Immunology Laboratory, Core Lab - AD3301, x1-3378
Turn-Around-Time
1-3 business days
Reference Values
< 7 U/mL = Negative
7-10 U/mL = Equivocal, should be repeated in 8-12 weeks
>10 U/mL = Positive