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Catalog ID FFTRP Trofile Co-Receptor Tropism Assay

Important Note

CPOE TEST NAME:  Ref Misc Referral Lab Test

Test Name REF:  Trofile 

Note: All orders for this test will undergo Pathology review for medical necessity.

Reporting Name

Trofile Phenotypic Corecept Tropism

Useful For

Detect HIV-1 coreceptor tropism; determine eligibility for CCR5 antagonist therapy such as maraviroc (Selzentry)


Specimen Required


Specimen Type: Plasma

Container/Tube: Lavender-top (EDTA) or plasma preparation tube (PPT)

Specimen Volume: 3 mL

Collection Instructions: Draw blood in either PPT (pearl top) or lavender-top (EDTA) tubes.

Centrifuge specimen within six hours of collection. Remove plasma from cells immediately, and transfer specimen to a screw-capped, plastic vial. Freeze 3 mL of PPT plasma or EDTA plasma immediately, send specimen frozen.

 

To avoid delays in turnaround time when requesting multiple tests, please submit separate frozen specimens for each test requested.

 

RECOMMENDED:

1.       Patient's most recent viral load

2.       Viral load collection date

 

Note:   1.  Intended to use only for patients with viral loads greater than or equal to 1000 copies/mL. For best results, viral loads should be confirmed within two weeks prior to submission for testing at Monogram.

           2.  Patient samples submitted <30 days apart are considered duplicate and will be cancelled.


AUMC Laboratory Catalog Note:

Collect 6.0 mL blood in Purple top tubes.

Day(s) Performed

Sunday through Saturday

Reject Due To

Other PPT not centrifuged; insufficient volume; heparinized plasma; non frozen specimens

Performing Laboratory

Monogram Biosciences, Inc

Specimen Type

Plasma EDTA

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen 14 days

CPT Code Information

87999

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FFTRP Trofile Phenotypic Corecept Tropism 57182-8

 

Result ID Test Result Name Result LOINC Value
Z1038 Tropotype Result 57182-8
Z1039 Note: Not Provided
Z1040 Activity of CCR5 antag anticipated? Not Provided

Method Name

Polymerase chain reaction (PCR) amplification and viral culture.

Report Available

29 to 39 days