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HelpCatalog ID EST FR Estrogens, Fractionated, by Mass Spectrometry
Additional Codes
CPOE: Ref Estrogens, Fractionated, by Mass Spectrometry
DOE: Ref Est Frac
Specimen
Gold SST tube, collect 1.0 mL blood
Centrifuge within 2 hours of specimen collection
Serum, 0.5 mL (0.3 mL minimum), refrigerated
Rejection Criteria
Specimens at room temperature >48 hours, specimens not centrifuged <2 hours from specimen collection, insufficient quantity, unlabelled specimen
Interpretative Information
Use to evaluate estrogen status in children, cisgender males, and postmenopausal cisgender females. Most useful when low estrogen concentrations are expected, regardless of the patient’s sex assigned at birth.
Performing Lab
ARUP Laboratories
Turn-Around-Time
1-4 days
Reference Values
| Component | Age | Male Reference Interval (pg/mL) | Female Reference Interval (pg/mL) |
|---|---|---|---|
| Estradiol by Mass Spec | 7-9 years | Less than 7.0 | Less than 36.0 |
| 10-12 years | Less than 11.0 | 1.0-87.0 | |
| 13-15 years | 1.0-36.0 | 9.0-249.0 | |
| 16-17 years | 3.0-34.0 | 2.0-266.0 | |
| 18 years and older | 10.0-42.0 | Early Follicular: 30.0-100.0 | |
| Late Follicular: 100.0-400.0 | |||
| Luteal: 50.0-150.0 | |||
| Postmenopausal: 2.0-21.0 | |||
| Tanner Stage I | Less than 8.0 | Less than 56.0 | |
| Tanner Stage II | Less than 10.0 | 2.0-133.0 | |
| Tanner Stage III | 1.0-35.0 | 12.0-277.0 | |
| Tanner Stage IV-V | 3.0-35.0 | 2.0-259.0 | |
| Estrone by Mass Spec | 7-9 years | Less than 7.0 | Less than 20.0 |
| 10-12 years | Less than 11.0 | 1.0-40.0 | |
| 13-15 years | 1.0-30.0 | 8.0-105.0 | |
| 16-17 years | 1.0-32.0 | 4.0-133.0 | |
| 18 years and older | 9.0-36.0 | Early Follicular: Less than 150.0 | |
| Late Follicular: 100.0-250.0 | |||
| Luteal: Less than 200.0 | |||
| Postmenopausal: 3.0-32.0 | |||
| Tanner Stage I | Less than 7.0 | Less than 27.0 | |
| Tanner Stage II | Less than 11.0 | 1.0-39.0 | |
| Tanner Stage III | 1.0-31.0 | 8.0-117.0 | |
| Tanner Stage IV-V | 2.0-30.0 | 4.0-109.0 | |
| Estrogens Total Calculation | 7-9 years | Less than 10.0 | 1.0-48.0 |
| 10-12 years | 1.0-19.0 | 2.0-116.0 | |
| 13-15 years | 3.0-62.0 | 15.0-333.0 | |
| 16-17 years | 4.0-64.0 | 6.0-354.0 | |
| 18 years or older | 19.0-69.0 | Early Follicular: 30.0-250.0 | |
| Late Follicular: 200.0-650.0 | |||
| Luteal: 50.0-350.0 | |||
| Postmenopausal: 5.0-52.0 | |||
| Tanner Stage I | 1.0-11.0 | 1.0-86.0 | |
| Tanner Stage II | 1.0-19.0 | 3.0-169.0 | |
| Tanner Stage III | 3.0-61.0 | 23.0-351.0 | |
| Tanner Stage IV-V | 4.0-62.0 | 8.0-341.0 |