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HelpCatalog ID Crohn Crohn Disease Prognostic Panel
Additional Codes
CPOE: Ref Crohn Disease Prognostic Panel
DOE: Ref Crohns
Reference Values
| Component | Reference Interval | Interpretation |
|---|---|---|
| Saccharomyces cerevisiae Ab (gASCA), IgG | 0-44 Units | Negative |
| 45-50 Units | Equivocal | |
| 51 Units or greater | Positive | |
| Laminaribioside Carbohydrate Ab ALCA IgG | 0-54 Units | Negative |
| 55-60 Units | Equivocal | |
| 61 Units or greater | Positive | |
| Mannobioside Carbohydrate Ab (AMCA), IgG | 0-89 Units | Negative |
| 90-100 Units | Equivocal | |
| 101 Units or greater | Positive | |
| Chitobioside Carbohydrate Ab (ACCA), IgA | 0-79 Units | Negative |
| 80-90 Units | Equivocal | |
| 91 Units or greater | Positive |
CPT Code
86671
83516 x 3
Specimen
Gold SST tube, collect 1.0 mL blood
0.5 mL serum, refrigerated
Rejection Criteria
Plasma, body fluids, grossly icteric, heat-inactivated, grossly hemolyzed, severely lipemic, contaminated, unlabelled, insufficient quantity
Interpretative Information
Anti-glycan serologic markers may serve as an aid in the diagnosis of Crohn disease (CD) and an indicator of disease prognosis. Anti-saccharomyces cerevisiae antibody (gASCA) has the highest diagnostic value and anti-chitobioside carbohydrate antibody (ACCA) has the highest association with more-aggressive disease. Both ACCA and gASCA are associated equally with the need for surgery. When found in combination, these markers have the best diagnostic potential. A combination of two or more of the four anti-glycan markers have a significant association with complications and the need for surgery than any single marker alone. A negative result does not rule out CD.
Performing Lab
ARUP Laboratories
Turn-Around-Time
1-8 Days