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HelpCatalog ID CarP Carbamylated Protein (CarP) Antibody, IgG
Additional Codes
CPOE: Ref Carbamylated Protein (CarP) Antibody, IgG
DOE: Ref CarP
Specimen
Gold SST tube, collect 1.0 mL blood
Centrifuge within 2 hours of specimen collection
Serum, 0.5 mL (0.3 mL minimum), refrigerated
Rejection Criteria
Plasma, contaminated specimen, heat-inactivated specimen, hemolyzed specimen, icteric specimen, lipemic specimen, specimen not centrifuged <2 hours from collection, room temperature specimen >48 hours after collection, insufficient quantity, unlabelled specimen
Interpretative Information
Anti-carbamylated protein (anti-CarP) IgG antibodies are present in about 34-53 percent of patients with RA, have specificities of greater than 90 percent and can occur in RA patients seronegative for both rheumatoid factor and anti-CCP. These autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.
Performing Lab
ARUP Laboratories
Turn-Around-Time
1-4 days
Reference Values
0-19 Units