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HelpCatalog ID Auto Neu CSF Autoimmune Neurologic Disease Panel With Reflex, CSF
Additional Codes
CPOE: Ref Autoimmune Neurologic Disease Panel With Reflex, CSF
DOE: Ref Auto Neu CSF
Specimen
CSF, four (4) 1.0 mL aliquots in transport tubes, frozen
Rejection Criteria
Fluid other than CSF, grossly hemolyzed specimens, insufficient quantity, unlabelled specimens
Interpretative Information
Comprehensive panel for the evaluation of paraneoplastic disorders and/or encephalitis in the presence or absence of malignancy.
If NMDA CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If AMPA CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If GABA-BR CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If CASPR2 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
PCCA/ANNA CSF antibodies are screened by IFA. If the IFA screen is indeterminate, then the Immunoblot will be added. If the IFA screen is positive at 1:1, then a specific titer (PCCA or ANNA) and Immunoblot will be added. Additional charges apply.
If LGI1 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If CV2.1 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If DPPX CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If ITPR1 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If IgLON5 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If GABA-AR CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If mGLUR1 antibody IgG is positive, then titer will be added. Additional charges apply.
Performing Lab
ARUP Laboratories
Turn-Around-Time
3-10 days (performed on Tuesdays)
Reference Values
| Component | Reference Interval |
|---|---|
| N-methyl-D-Aspartate Receptor Ab, CSF | Less than 1:1 |
| Paraneoplastic Abs (PCCA/ANNA) IgG, CSF | None Detected |
| AMPA Receptor Ab IgG Screen, CSF | Less than 1:1 |
| GABA-B Receptor Ab IgG Screen, CSF | Less than 1:1 |
| CASPR2 Ab IgG Screen by IFA, CSF | Less than 1:1 |
| Voltage-Gated Potassium Channel Ab, CSF | Less than 1:1 |
| LGI1 Ab IgG Screen by IFA, CSF | Less than 1:1 |
| CV2.1 Ab IgG Screen, CSF | Less than 1:1 |
| Glutamic Acid Decarboxylase Antibody CSF | 0.0-5.0 IU/mL |
| SOX1 Antibody, IgG by Immunoblot, CSF | Negative |
| Amphiphysin Antibody, CSF | Negative |
| DPPX Ab IgG CBA IFA Screen, CSF | Less than 1:1 |
| ITPR1 Ab IgG CBA-IFA Screen, CSF | Less than 1:1 |
| IgLON5 Ab IgG CBA-IFA Screen, CSF | Less than 1:1 |
| GABA-AR Ab IgG CBA-IFA Screen, CSF | Less than 1:1 |
| mGluR1 Ab IgG CBA-IFA Screen, CSF | Less than 1:1 |