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Catalog ID Auto Enc CSF Autoimmune Encephalitis Reflex Panel, CSF

Important Note

This test will be discontinued by ARUP effective 5/20/24. Please order a symptom specific autoimmune panel.

Additional Codes

CPOE: Ref Autoimmune Encephalitis Reflex Panel, CSF

DOE: Ref Auto Enc CSF

Specimen

CSF, three (3) 1.0 mL aliquots in separate transport tubes, frozen

Rejection Criteria

Non-CSF specimen, contaminated specimen, specimen at room temperature >24 hours, specimen refrigerated >7 days, insufficient quantity, unlabelled specimen

Interpretative Information

Aids in the differential evaluation of encephalitis of unknown origin with subacute onset of seizures, confusion, memory loss, and/or behavioral change.

If NMDA CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If AQP4 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If AMPA CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If GABA-BR CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If CASPR2 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If LGI1 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If DPPX CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If IgLON5 CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If GABA-AR CSF antibody IgG is positive, then titer will be added. Additional charges apply.
If mGluR1 CSF antibody IgG is positive, then titer will be added. Additional charges apply.

Performing Lab

ARUP Laboratories

Turn-Around-Time

3-10 days (performed on Tuesdays)

Reference Values

Component Reference Interval
Glutamic Acid Decarboxylase Antibody CSF 0.0-5.0 IU/mL
N-methyl-D-Aspartate Receptor Ab, CSF Less than 1:1
Neuromyelitis Optica/AQP4-IgG, CSF Less than 1:1
AMPA Receptor Ab IgG Screen, CSF Less than 1:1
GABA-B Receptor Ab IgG Screen, CSF Less than 1:1
Voltage-Gated Potassium Channel Ab, CSF Less than 1:1
CASPR2 Ab IgG Screen by IFA, CSF Less than 1:1
LGI1 Ab IgG Screen by IFA, CSF Less than 1:1
DPPX Ab IgG CBA IFA Screen, CSF Less than 1:1
IgLON5 Ab IgG CBA-IFA Screen, CSF Less than 1:1
GABA-AR Ab IgG CBA-IFA Screen, CSF Less than 1:1
mGluR1 Ab IgG CBA-IFA Screen, CSF Less than 1:1