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HelpCatalog ID AFPSF Alpha-Fetoprotein (AFP), Spinal Fluid
Reporting Name
Alpha-Fetoprotein, CSFUseful For
An adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis
Evaluating the presence of germ-cell tumors in the CNS, in conjunction with cerebrospinal fluid (CSF) beta-human chorionic gonadotropin measurement
A supplement to CSF cytologic analysis
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
CSFSpecimen Required
Container/Tube: Sterile vial
Preferred: Vial number 1
Acceptable: Any vial
Specimen Volume: 1 mL
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Frozen (preferred) | 7 days | |
| Refrigerated | 7 days |
Reference Values
<1.5 ng/mL
Values for alpha-fetoprotein in cerebrospinal fluid have not been formally established for newborns and infants. The available literature indicates that by 2 months of age, levels comparable to adults should be reached.(Ann Clin Biochem 2005;42:24-29)
Day(s) Performed
Monday through Saturday
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86316
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AFPSF | Alpha-Fetoprotein, CSF | 1833-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AFSF | Alpha-Fetoprotein, CSF | 1833-3 |
Report Available
1 to 3 daysReject Due To
| Gross hemolysis | Reject |
| Gross icterus | OK |
Method Name
Immunoenzymatic Assay
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.