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Catalog ID 7AC4 7AC4, Bile Acid Synthesis, Serum

Important Note

This test is never covered by insurance. Patients either will be required to pay prior or will receive a bill for $208.50 for this test.

Additional Codes

Order: Ref Specimen Referral Misc

Comment: 7AC4 Bile Acid Synthesis

Note: All orders for this test will undergo Pathology review for medical necessity.

Useful For

Screening for bile acid malabsorption in patients with irritable bowel syndrome with diarrhea


Specimen Required


Patient Preparation:

1. Patient must fast for at least 12 hours prior to collection; fasting morning specimen is preferred.

2. Patient should not be taking bile acid sequestrants for 24 hours prior to collection or statins for 5 days prior to collection.

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge and aliquot 1 mL of serum into plastic vial.

2. Send specimen frozen.


AUMC Laboratory Catalog Note:

Collect 2.0 mL blood in Gold top tube. Patient should be fasting for at least 12 hours prior to draw and not taking PPIs or statins.

Reference Values

≥18 years: 2.5-63.2 ng/mL

Reference values have not been established for patients who are <18 years of age.

Day(s) Performed

Monday, Thursday

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

7AC4, Bile Acid Synthesis, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 90 days
  Refrigerated  72 hours
  Ambient  24 hours

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Secondary ID

607699

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
7AC4 7AC4, Bile Acid Synthesis, S 94866-1

 

Result ID Test Result Name Result LOINC Value
65504 7AC4, Bile Acid Synthesis, S 94866-1

Forms

If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen

Report Available

5 days

Testing Algorithm

For more information see Ordering Guide: Bile Acid-Associated Tests.